Coffee is one of the most popular beverages in the world.

Image Credit: Stockbyte/Stockbyte/Getty Images For many, coffee is an eye opener, a pleasant break or a way to make a social connection. However, anxiety and irritability sometimes occur in conjunction with drinking coffee. People who are not regular coffee drinkers are more prone to these side effects, according to an August 2010 study report published in “Neuropsychopharmacology.” A number of reseach studies have examined this relationship. Coffee contains many chemicals, but caffeine is the one responsible for causing anxiety and irritability.

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Caffeine and Irritabilty

Irritability is an unpleasant feeling of being overly sensitive to stimulation and easily annoyed. The caffeine found in coffee can produce a heightened sense of perception by stimulating the brain. This effect makes a person more aware of mild annoyances, thereby increasing irritability. Caffeine withdrawal in someone used to consuming large amounts of coffee or other caffeinated beverages can also cause irritability.

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Caffeine and Anxiety

Anxiety is a sense of apprehension and unease. The same chemical process in the brain that causes the benefits of intensified alertness can actually serve as a double-edged sword, increasing anxiety by making you more aware of all the potential negative outcomes in a situation.

Variable Responses

The impact of coffee on anxiety and irritability is individualized. The chemicals in coffee trigger a range of emotional responses, depending on a person’s coffee drinking habits, body weight, metabolism and baseline mood. People who have had less exposure to caffeine or who regularly experience more than usual anxiety and irritability – even in the absence of coffee – tend to have a stronger response to the effects of coffee. There is also a genetic component to an individual’s response to coffee intake.

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  references
  
      Today's Dietitian: Cortisol -- Its Role in Stress, Inflammation and Indications for Diet Therapy
    
      PLOS One: Caffeine Improves Left Hemisphere Processing of Positive Words
    
      Social Cognitive and Affective Neuroscience: Storm in a Coffee Cup -- Caffeine Modifies Brain Activation to Social Signals of Threat
    
      Psychopharmacology: Genetics of Caffeine Consumption and Responses to Caffeine
    
      Neuropsychopharmacology: Association of the Anxiogenic and Alerting Effects of Caffeine With ADORA2A and ADORA21 Polymorphisms and Habitual Level of Caffeine Consumption
    
      Psychiatry Research: Panic Disorder and Social Anxiety Disorder Subtypes in a Caffeine Challenge Test
    
      BMC Public Health: Water and Beverage Consumption Among Adults in the United States -- Cross-sectional Study Using Data From NHANES 2005–2010
    
      Current Opinion in Clinical Nutritional Metabolic Care: Coffee and Tea -- Perks for Health and Longevity?
       




  references
  
      Today's Dietitian: Cortisol -- Its Role in Stress, Inflammation and Indications for Diet Therapy
    
      PLOS One: Caffeine Improves Left Hemisphere Processing of Positive Words
    
      Social Cognitive and Affective Neuroscience: Storm in a Coffee Cup -- Caffeine Modifies Brain Activation to Social Signals of Threat
    
      Psychopharmacology: Genetics of Caffeine Consumption and Responses to Caffeine
    
      Neuropsychopharmacology: Association of the Anxiogenic and Alerting Effects of Caffeine With ADORA2A and ADORA21 Polymorphisms and Habitual Level of Caffeine Consumption
    
      Psychiatry Research: Panic Disorder and Social Anxiety Disorder Subtypes in a Caffeine Challenge Test
    
      BMC Public Health: Water and Beverage Consumption Among Adults in the United States -- Cross-sectional Study Using Data From NHANES 2005–2010
    
      Current Opinion in Clinical Nutritional Metabolic Care: Coffee and Tea -- Perks for Health and Longevity?
    




Coffee is one of the most popular beverages in the world.

Image Credit: Stockbyte/Stockbyte/Getty Images

Image Credit: Stockbyte/Stockbyte/Getty Images

      Today's Dietitian: Cortisol -- Its Role in Stress, Inflammation and Indications for Diet Therapy
    
      PLOS One: Caffeine Improves Left Hemisphere Processing of Positive Words
    
      Social Cognitive and Affective Neuroscience: Storm in a Coffee Cup -- Caffeine Modifies Brain Activation to Social Signals of Threat
    
      Psychopharmacology: Genetics of Caffeine Consumption and Responses to Caffeine
    
      Neuropsychopharmacology: Association of the Anxiogenic and Alerting Effects of Caffeine With ADORA2A and ADORA21 Polymorphisms and Habitual Level of Caffeine Consumption
    
      Psychiatry Research: Panic Disorder and Social Anxiety Disorder Subtypes in a Caffeine Challenge Test
    
      BMC Public Health: Water and Beverage Consumption Among Adults in the United States -- Cross-sectional Study Using Data From NHANES 2005–2010
    
      Current Opinion in Clinical Nutritional Metabolic Care: Coffee and Tea -- Perks for Health and Longevity?